A single 150 mg oral dose is the standard fluconazole dosage for uncomplicated vaginal yeast infections, while 200 mg daily is used for infections in the mouth, esophagus, or deeper tissues. Detailed dosage guidelines and administration information for Diflucan (fluconazole). Includes dose adjustments, warnings and precautions. The dose is usually 12 milligrams (mg) per kilogram (kg) of body weight on the first day, followed by 6 mg per kg of body weight once a day, for at least 10 to 12 weeks. The typical Diflucan dosage for adults ranges from 50 mg to 400 mg daily. The oral tablet is most common, but if you have difficulty swallowing medications, the oral suspension is another option. Detailed Fluconazole dosage information for adults and children. Includes dosages for Vaginal Candidiasis, Onychomycosis - Toenail, Oral Thrush and more; plus renal, liver and dialysis adjustments. Find patient medical information for Fluconazole (Diflucan) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Medically reviewed guide to fluconazole (Diflucan) dosages. Find typical strengths for adults and children, treatment lengths, and tips for taking oral tablets safely. Medscape - Candidia infection dosing for Diflucan (fluconazole), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost. The recommended dosage of DIFLUCAN for esophageal candidiasis is 200 mg on the first day, followed by 100 mg once daily. Doses up to 400 mg/day may be used, based on medical judgment of the patient's response to therapy. Since Diflucan is eliminated primarily through the kidneys, dose adjustments are necessary for patients with renal dysfunction. Typically, the dose or dosing interval is reduced to prevent accumulation and toxicity.